The Role of FFPE Blocks in Molecular Diagnostics
Preservation of Tissue Samples
FFPE blocks serve as custodians of biological specimens, ensuring their long-term preservation. The process involves fixing tissues in formalin, preventing decay and maintaining cellular structures for extended periods.
DNA and RNA Extraction
The embedded tissues in FFPE blocks facilitate the extraction of DNA and RNA, enabling researchers to explore the genetic underpinnings of diseases. This extraction process forms the foundation for various molecular diagnostic techniques.
Historical Significance
Beyond their contemporary significance, FFPE blocks carry historical value, housing archives of invaluable tissue samples. This historical repository aids in retrospective studies and benchmarking diagnostic advancements over time.
Advantages of Using FFPE Blocks in Molecular Diagnostics
Long-term Tissue Storage
The longevity of FFPE blocks allows for prolonged storage of tissues, creating a valuable resource for researchers studying diseases with long incubation periods or gradual progression.
Sample Integrity
FFPE blocks maintain the integrity of samples, preserving cellular morphology. This is particularly crucial for diagnostic accuracy and subsequent research endeavors.
Accessibility for Research
The widespread use of FFPE blocks enhances accessibility for researchers, fostering collaborative efforts and contributing to the collective knowledge in molecular diagnostics.
